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Experimental cardio-oncology

ImmunoMet

Welcome to the ImmunoMet laboratory. We are researching the metabolic control of T cells and investigating how nutrition and metabolism regulate the various functions of the immune system.

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Research on nutrition & metabolism

These connections are crucial for health, because the metabolism of an individual immune cell is closely linked to the metabolism of the entire body. We have recently shown that different metabolic pathways in so-called "unconventional T cells" direct their function towards proinflammatory and antitumor or regulatory and reparative phenotypes. One focus of our work is the metabolically competitive microenvironment of tumors and cardiovascular diseases characterized by dyslipidemia.

By understanding how systemic nutrient status, tissue-specific metabolic signals and cellular metabolic programs interact to control T cell functions, we can specifically modulate immune responses, optimize metabolic health and develop new therapeutic approaches.

Quote Prof. Dr. Thomas Riffelmacher

The Immunomet laboratory was established with the support of the Marga and Walter Boll Foundation.